Genetic Engineering In Animals Research Essay
1. World Health Organisation (OIE) Definition of animal welfare, glossary. 2010. Terrestrial Animal Health Code; p. xiv.
2. MacArthur JA, Potter M, Harding E. The welfare implications of animal breeding and breeding technologies in commercial agriculture. Livestock Sci. 2006;103:270–281.
3. United States Department of Energy Genome Projects. Cloning Fact Sheet 2009. [Last accessed March 16, 2011]. Available from www.ornl.gov/hgmis/elsi/cloning.shtml.
4. Wilmut I, Beaujean N, de Sousa PA, et al. Somatic cell nuclear transfer. Nature. 2002;419:583–587.[PubMed]
5. West C. Economic and ethics in the genetic engineering of animals. Harvard J Law Technol. 2006;19:413–442.
6. Shin T, Kraemer D, Pryor J, et al. Cell biology: A cat cloned by nuclear transplantation. Nature. 2002;415:859.[PubMed]
7. Lee BC, Kim MK, Jang G, et al. Dogs cloned from adult somatic cells. Nature. 2005;436:641.[PubMed]
8. Holt WV, Pickard AR, Prather RS. Wildlife conservation and reproductive cloning. Reproduction. 2004;127:317–324.[PubMed]
9. Laible G. Enhancing livestock through genetic engineering — Recent advances and future prospects. Comp Immunol Microb. 2009;32:123–127.[PubMed]
10. Gaskell G, Allum N, Stares S. Europeans and Biotechnology in 2002: Eurobarometer 58.0 2003. Directorate General Press and Communication, Public Opinion Analysis Unit;
11. Food and Drug Administration (FDA) US Environmental assessment for AquAdvantage® salmon. FDA Report August 25, 2010. [Last accessed March 16, 2011]. Available from: http://www.fda.gov/downloads/AdvisoryCommittees/CommitteesMeetingMaterials/VeterinaryMedicineAdvisoryCommittee/UCM224760.pdf.
12. Dyck MK, Lacroix D, Pothier F, Sirard M-A. Making recombinant proteins in animals — different systems, different applications. Trends Biotechnol. 2003;21:394–399.[PubMed]
13. Wells DJ. Genetically modified animals and pharmacological research. In: Cunningham F, Elliot J, Lees P, editors. Comparative and Veterinary Pharmacology. Berlin: Springer; 2010. pp. 213–226. [PubMed]
14. Rudmann DG, Durham SK. Utilization of genetically altered animals in the pharmaceutical industry. Toxicol Pathol. 1999;27:111–114.[PubMed]
15. Logan JS, Sharma A. Potential use of genetically modified pigs as organ donors for transplantation into humans. Clin Exp Pharmacol P. 1999;26:1020–1025.[PubMed]
16. Einsiedel EF, Ross H. Animal spare parts? A Canadian public consultation on xenotransplantation. Sci Eng Ethics. 2002;8:579–591.[PubMed]
17. Fenwick N, Griffin G, Gauthier C. The welfare of animals used in science: How the “Three Rs” ethic guides improvements. Can Vet J. 2009;50:523–530.[PMC free article][PubMed]
18. Macnaghten P. Animals in their nature: A case study of public attitudes to animals, genetic modification and “nature. Sociology. 2004;38:533–551.
19. Robinson V, Morton DB, Anderson D, et al. Refinement and reduction in production of genetically modified mice. Sixth report of the BVAAWF/FRAME/RSPCA/UFAW Joint Working Group on Refinement. 2003. [Last accessed March 16, 2011]. Available from: http://www.arsal.ro/wp-content/uploads/members/13.%20Refinement%20and%20reduction%20in%20production%20of%20genetically%20modified%20mice.pdf.
20. Ormandy EH. The use of genetically-engineered animals in science. A report from the Third Genome BC Knowledge Translation Workshop; Vancouver BC. March 15, 2010; [accessed March16, 2011]. Available from: http://www.genomebc.ca/portfolio/genomics-and-society/events/knowledge-translation-workshops/genetically-engineered-animals/Last.
21. Ormandy EH, Schuppli CA, Weary DM. Worldwide trends in the use of animals in research: The contribution of genetically modified animal models. ATLA. 2009;37:63–68.[PubMed]
22. Osborne N, Jackson I, Cox D, et al. Sharing and archiving of genetically altered mice: Opportunities for reduction and refinement. A report of the RSPCA Resource Sharing Working Group (RSWG) 2009. [Last accessed March 16, 2011]. Available from http://www.nc3rs.org.uk/downloaddoc.asp?id=857.
23. Canadian Council on Animal Care. Trends in Animal Use. 2008. [Last accessed March 20, 2011]. Available from http://www.ccac.ca/Documents/Publications/Statistics/Survey_2009.pdf.
24. Gauthier C. Overview and analysis of animal use in North America. ATLA. 2004;32(Suppl 1A):275–285.[PubMed]
25. Department for Environment, Food and Rural Affairs (DEFRA) Policy on the use of animals in research. 2004. [Last accessed March 16, 2011]. Available from http://www.defra.gov.uk/science/documents/Defra-Policy_%20On_Use_Of_Animals_In_Research.pdf.
26. Verbeek JS. Scientific applications of transgenic mouse models. In: Van Zutphen LFM, Van Der Meer M, editors. Welfare Aspects of Transgenic Animals — Proceedings EC Workshop. Berlin: Springer-Verlag; 1997. pp. 1–17.
27. Yoshiki A, Moriwaki K. Mouse phenome research: Implications of genetic background. ILAR. 2006;47(2):94–102.[PubMed]
28. Weaver SA, Morris MC. Risks associated with genetic modification: An annotated bibliography of peer reviewed natural science publications. J Agr Enviro Ethic. 2005;18:157–189.
29. Wells DJ, Playle LC, Enser WEJ, et al. Assessing the welfare of genetically altered mice. Lab Anim. 2006;40:111–114.[PubMed]
30. Miller JC, Holmes MC, Wang J, et al. An improved zinc-finger nuclease technology architecture for highly specific genome editing. Nat Biotechnol. 2007;25:778–785.[PubMed]
31. Yang GS, Banks KG, Bonaguro RJ, et al. Next generation tools for high-throughput promoter and expression analysis employing single-copy knock-ins at the Hprt1 locus. Genomics. 2009;93:196–204.[PubMed]
32. Lassen J, Gjerris M, Sandoe P. After Dolly — ethical limits to the use of biotechnology on farm animals. Theriogenology. 2006;65:992–1004.[PubMed]
33. Oritz G, Elizabeth S. Beyond welfare: Animal integrity, animal dignity, and genetic engineering. Ethic Enviro. 2004;9:94–120.
34. Rollin BE. On telos and genetic-engineering. In: Armstrong SJ, Botzler RG, editors. Animal Ethics Reader. London, UK: Routledge; 2003. pp. 342–350.
35. Veerhoog H. The concept of intrinsic value and transgenic animals. J Agr Ethics. 1992:147–160.[PubMed]
36. Schicktanz S. Ethical considerations of the human-animal-relationship under conditions of asymmetry and ambivalence. J Agr Enviro Ethic. 2006;19:7–16.
37. Schuppli CA, Weary DM. Attitudes towards the use of genetically-modified animals in research. Public Understanding of Science. 2010;19:686–697.[PubMed]
Genetic Engineering Essay
986 Words4 Pages
Many scientists today are all trying to prefect the studies of genetic engineering, also known as cloning. This has become one of the most popular studies of this decade. Scientist says that with genetic engineering the human race can live forever. For some people cloning could be the greatest experiment of all time, but also it could be the most dangerous and harmful experiment that was ever attempted. Why do we feel the need to clone humans, animals? Should we just let human live and die just like god intended or should we try to be immortal? As you read on you the reader decides if genetic engineering is the greatest experiment we ever attempted or should we band cloning forever.
According to B. Julie…show more content…
DNA is substance that encodes genetic information passed from one generation to the next. By using DNA scientist are able to cross plants for example crossing pea plants to make different types of plants. Experimenters can also cross bread in ways that were unimaginable to humans. For example cross human DNA with a pig, they also crossed DNA strands with a cow and a fish. Some scientists have been awarded for the strange crossing of DNA strands for having come up with a way to genetically engineer those uncommon life forms. They also get Pantene for those weird cross breads like it was an invention. Not all experiments are successful though. Dr. John Haster a cofounder of an animal biomechanical company of Pennsylvania was never made by nature. There are very many deformations that animals go through that affect the way they live and when the animal starts to grow up they go through torture. So why do they keep doing all these curl experiment on animals will this benefit use in the future? A lot of people are asking them selves if scientists are trying to play god. To many people who care about humans and are future say that many scientists are. People say that we should just live and die just like god intended. The scientist that perform these experiments say that if god wanted that he would never have gave us this major break through and new ideas to help the human race live longer and healthier. Dr Edwin Chagaff, professor Emirtitos of biochemistry at Columbia